A Mouse Model of Anaphylaxis and Atopic Dermatitis to Salt-Soluble Wheat Protein Extract

Background: Wheat allergy and other immune-mediated disorders triggered by wheat proteins are growing at an alarming rate for reasons not well understood. A mouse model to study hypersensitivity responses to salt-soluble wheat protein (SSWP) extract is currently unavailable. Here we tested the hypot...

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Veröffentlicht in:	International archives of allergy and immunology 2017-10, Vol.174 (1), p.7-16
Hauptverfasser:	Jin, Yining, Ebaugh, Sarah, Martens, Anna, Gao, Haoran, Olson, Eric, Ng, Perry K.W., Gangur, Venu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Adhesion tests Alum Aluminum sulfate Anaphylaxis Anaphylaxis - immunology Animal tissues Animals Antibodies - blood Atopic dermatitis Blood Cell adhesion & migration Cell Degranulation - immunology Chemical properties Chemokines Chymases - blood Correlation analysis Cytokines Degranulation Dermatitis Dermatitis - immunology Dermatitis, Atopic - immunology Development and progression Disease Models, Animal E-selectin Eczema Enzyme-linked immunosorbent assay Female Glutens - immunology Health aspects Helper cells Histopathology Hypersensitivity Hypothermia Immunoglobulin E Immunoglobulin E - blood Injection Lesions Lymphocytes T Mast Cells - immunology Mice Mice, Inbred BALB C Molecules and Cells in Allergy - Original Paper Mucosa Protein arrays Proteins Risk factors Rodents Salts Silicon germanides Skin Th1 Cells - immunology Th17 Cells - immunology Th2 Cells - immunology Triticum - immunology Wheat Wheat Hypersensitivity - immunology
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