Comparison of Effects of Perflubron and Surfactant Lung Lavage on Pulmonary Gas Exchange in a Piglet Model of Meconium Aspiration

In a piglet model of meconium aspiration we compared lavage with surfactant with that with perflubron (PFOB) and a control group. A human meconium suspension was instilled into piglets which were randomized in 3 (n = 6 each) groups. After lung injury, the control group was ventilated with high-frequ...

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Veröffentlicht in:	Biology of the neonate 2002-01, Vol.81 (2), p.126-131
Hauptverfasser:	Schlösser, Rolf L., Veldman, Alex, Fischer, Doris, Funk, Benjamin, Brand, Jörg, von Loewenich, Volker
Format:	Artikel
Sprache:	eng
Schlagworte:	Air breathing Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Animals, Newborn Biological and medical sciences Bronchoalveolar Lavage Disease Models, Animal Emergency and intensive care: neonates and children. Prematurity. Sudden death Fluorocarbons - pharmacology Fundamental and applied biological sciences. Psychology High-Frequency Ventilation Histocytochemistry Humans Infant, Newborn Intensive care medicine Meconium Aspiration Syndrome - drug therapy Meconium Aspiration Syndrome - pathology Meconium Aspiration Syndrome - therapy Medical sciences Original Paper Pulmonary Gas Exchange - drug effects Random Allocation Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics Statistics, Nonparametric Surface-Active Agents - pharmacology Swine Swine Diseases - pathology Swine Diseases - therapy Vertebrates: respiratory system
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