Effects of Distigmine on Electrical Field Stimulation-Induced Contraction of Mouse Urinary Bladder Smooth Muscles

Distigmine bromide (distigmine), a reversible carbamate cholinesterase inhibitor, is used in Japan for treating detrusor underactivity, myasthenia gravis, and glaucoma. Although there is clinical evidence about the effectiveness of distigmine in the treatment of detrusor underactivity, mechanisms by...

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Veröffentlicht in:	Pharmacology 2017-01, Vol.99 (3-4), p.106-113
Hauptverfasser:	Obara, Keisuke, Kobayashi, Yurina, Chino, Daisuke, Tanaka, Yoshio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cholinesterase Inhibitors - pharmacology Electric Stimulation - methods Male Mice Muscle Contraction - drug effects Muscle Contraction - physiology Muscle, Smooth - drug effects Muscle, Smooth - physiology Organ Culture Techniques Pyridinium Compounds - pharmacology Short Communications Urinary Bladder - drug effects Urinary Bladder - physiology
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