Antiherpetic Mechanism of a Sulfated Derivative of Agaricus brasiliensis Fruiting Bodies Polysaccharide

Objective: To study the anti-herpes simplex virus (HSV) activity of a (1→6)-(1→3)-β- D -glucan isolated from Agaricus brasiliensis fruiting bodies (FR) as well as its chemically sulfated derivative (FR-S). Methods: The antiherpetic activity and mechanism of action was studied by viral plaque assay a...

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Veröffentlicht in:	Intervirology 2014-01, Vol.57 (6), p.375-383
Hauptverfasser:	Cardozo, Francielle Tramontini Gomes de Sousa, Camelini, Carla Maísa, Leal, Paulo César, Kratz, Jadel Müller, Nunes, Ricardo José, Mendonça, Margarida Matos de, Simões, Cláudia Maria Oliveira
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyclovir - pharmacology Agaricus - chemistry Animals Antiviral Agents - chemistry Antiviral Agents - pharmacology beta-Glucans - chemistry beta-Glucans - isolation & purification beta-Glucans - pharmacology Brazil Cercopithecus aethiops Drug Synergism Fruiting Bodies, Fungal - chemistry Herpesvirus 1, Human - drug effects Herpesvirus 2, Human - drug effects Original Paper Polysaccharides - chemistry Polysaccharides - pharmacology Vero Cells Viral Plaque Assay
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