Lymphocyte Levels of Redox-Sensitive Transcription Factors and Antioxidative Enzymes as Indicators of Pro-Oxidative State in Depressive Patients

Background: Oxidative stress is reliably observed in major depressive disorder (MDD). However, molecular data on the principal cellular redox-sensitive transcriptional factors and the levels of their downstream-regulated antioxidant enzymes in MDD are scarce. Methods: In the peripheral blood mononuc...

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Veröffentlicht in:	Neuropsychobiology 2014-01, Vol.70 (1), p.1-9
Hauptverfasser:	Lukic, Iva, Mitic, Milos, Djordjevic, Jelena, Tatalovic, Nikola, Bozovic, Natalija, Soldatovic, Ivan, Mihaljevic, Marina, Pavlovic, Zorana, Radojcic, Marija B., Maric, Nadja P., Adzic, Miroslav
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antioxidants - metabolism Catalase Depressive Disorder - pathology Female Gene Expression Regulation - physiology Glutathione Peroxidase Glutathione Reductase Humans Intracellular Signaling Peptides and Proteins - metabolism Kelch-Like ECH-Associated Protein 1 Lymphocytes - metabolism Male Middle Aged NF-E2-Related Factor 2 - metabolism NF-kappa B - metabolism Original Paper Oxidation-Reduction Oxidative Stress - physiology Superoxide Dismutase - metabolism
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