Results of Construction of Protective Loop Ileostomies and Reversal Surgery for Colorectal Surgery
Background: Protective loop ileostomies in colorectal surgery are constructed to reduce morbidity and reinterventions related to the primary operation. However, ileostomies are associated with stoma-related morbidity and postoperative complications following reversal surgery. Dutch national data sho...
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Veröffentlicht in: | European surgical research 2014-01, Vol.52 (1-2), p.63-72 |
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description | Background: Protective loop ileostomies in colorectal surgery are constructed to reduce morbidity and reinterventions related to the primary operation. However, ileostomies are associated with stoma-related morbidity and postoperative complications following reversal surgery. Dutch national data show increased use of loop ileostomies in colorectal surgery for cancer justifying an adequate assessment of its morbidity. This study was undertaken to investigate morbidity associated with protective loop ileostomies in colorectal surgery. Methods: Retrospectively, 118 consecutive patients undergoing left-sided colonic or rectal resection with protective loop ileostomy were included. Primary outcome was 30-day mortality. Secondary endpoints included total complication rate (including stoma-related morbidity), total reintervention risk, anastomotic leakage risk and total length of stay. Results: No mortality was observed. Overall major complication, reintervention and anastomotic leakage risk for colorectal surgery were 20, 20 and 3.9%, respectively. Combined length of stay for stoma-related morbidity and reversal surgery was 12.7 days. The risk for stoma-related morbidity was 35%, and the risk for nonelective reversal was 12%. Closure rate (mean follow-up of 15 months) was 87% with a mean interval of 125 days. Reversal surgery was not correlated with mortality but with major complications (11%) and reintervention risk, anastomotic leakage risk (3.8%) and a mean length of stay of 9 days. Conclusion: Construction of loop ileostomies in left-sided colonic or rectal resection is associated with a low risk for anastomotic leakage at the expense of substantial stoma-related morbidity and morbidity related to reversal surgery. More accurate identification of colorectal cancer patients benefitting from protective loop ileostomy seems to be warranted. |
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However, ileostomies are associated with stoma-related morbidity and postoperative complications following reversal surgery. Dutch national data show increased use of loop ileostomies in colorectal surgery for cancer justifying an adequate assessment of its morbidity. This study was undertaken to investigate morbidity associated with protective loop ileostomies in colorectal surgery. Methods: Retrospectively, 118 consecutive patients undergoing left-sided colonic or rectal resection with protective loop ileostomy were included. Primary outcome was 30-day mortality. Secondary endpoints included total complication rate (including stoma-related morbidity), total reintervention risk, anastomotic leakage risk and total length of stay. Results: No mortality was observed. Overall major complication, reintervention and anastomotic leakage risk for colorectal surgery were 20, 20 and 3.9%, respectively. Combined length of stay for stoma-related morbidity and reversal surgery was 12.7 days. The risk for stoma-related morbidity was 35%, and the risk for nonelective reversal was 12%. Closure rate (mean follow-up of 15 months) was 87% with a mean interval of 125 days. Reversal surgery was not correlated with mortality but with major complications (11%) and reintervention risk, anastomotic leakage risk (3.8%) and a mean length of stay of 9 days. Conclusion: Construction of loop ileostomies in left-sided colonic or rectal resection is associated with a low risk for anastomotic leakage at the expense of substantial stoma-related morbidity and morbidity related to reversal surgery. More accurate identification of colorectal cancer patients benefitting from protective loop ileostomy seems to be warranted.</description><identifier>ISSN: 0014-312X</identifier><identifier>EISSN: 1421-9921</identifier><identifier>DOI: 10.1159/000357053</identifier><identifier>PMID: 24777108</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Aged ; Anastomotic Leak - etiology ; Anastomotic Leak - prevention & control ; Colonic Neoplasms - surgery ; Digestive System Surgical Procedures - adverse effects ; Digestive System Surgical Procedures - methods ; Digestive System Surgical Procedures - mortality ; Female ; Humans ; Ileostomy - adverse effects ; Ileostomy - methods ; Ileostomy - mortality ; Length of Stay ; Male ; Middle Aged ; Netherlands - epidemiology ; Original Paper ; Rectal Neoplasms - surgery ; Reoperation - adverse effects ; Reoperation - methods ; Retrospective Studies</subject><ispartof>European surgical research, 2014-01, Vol.52 (1-2), p.63-72</ispartof><rights>2014 S. Karger AG, Basel</rights><rights>2014 S. Karger AG, Basel.</rights><rights>Copyright (c) 2014 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c428t-aed92bd3e0baa2fd61354647b78db05081dd143694336859e561642ee0e291503</citedby><cites>FETCH-LOGICAL-c428t-aed92bd3e0baa2fd61354647b78db05081dd143694336859e561642ee0e291503</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,2423,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24777108$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Abegg, R.M.</creatorcontrib><creatorcontrib>Brokelman, W.</creatorcontrib><creatorcontrib>van Bebber, I.P.</creatorcontrib><creatorcontrib>Bosscha, K.</creatorcontrib><creatorcontrib>Prins, H.A.</creatorcontrib><creatorcontrib>Lips, D.J.</creatorcontrib><title>Results of Construction of Protective Loop Ileostomies and Reversal Surgery for Colorectal Surgery</title><title>European surgical research</title><addtitle>Eur Surg Res</addtitle><description>Background: Protective loop ileostomies in colorectal surgery are constructed to reduce morbidity and reinterventions related to the primary operation. However, ileostomies are associated with stoma-related morbidity and postoperative complications following reversal surgery. Dutch national data show increased use of loop ileostomies in colorectal surgery for cancer justifying an adequate assessment of its morbidity. This study was undertaken to investigate morbidity associated with protective loop ileostomies in colorectal surgery. Methods: Retrospectively, 118 consecutive patients undergoing left-sided colonic or rectal resection with protective loop ileostomy were included. Primary outcome was 30-day mortality. Secondary endpoints included total complication rate (including stoma-related morbidity), total reintervention risk, anastomotic leakage risk and total length of stay. Results: No mortality was observed. Overall major complication, reintervention and anastomotic leakage risk for colorectal surgery were 20, 20 and 3.9%, respectively. Combined length of stay for stoma-related morbidity and reversal surgery was 12.7 days. The risk for stoma-related morbidity was 35%, and the risk for nonelective reversal was 12%. Closure rate (mean follow-up of 15 months) was 87% with a mean interval of 125 days. Reversal surgery was not correlated with mortality but with major complications (11%) and reintervention risk, anastomotic leakage risk (3.8%) and a mean length of stay of 9 days. Conclusion: Construction of loop ileostomies in left-sided colonic or rectal resection is associated with a low risk for anastomotic leakage at the expense of substantial stoma-related morbidity and morbidity related to reversal surgery. More accurate identification of colorectal cancer patients benefitting from protective loop ileostomy seems to be warranted.</description><subject>Aged</subject><subject>Anastomotic Leak - etiology</subject><subject>Anastomotic Leak - prevention & control</subject><subject>Colonic Neoplasms - surgery</subject><subject>Digestive System Surgical Procedures - adverse effects</subject><subject>Digestive System Surgical Procedures - methods</subject><subject>Digestive System Surgical Procedures - mortality</subject><subject>Female</subject><subject>Humans</subject><subject>Ileostomy - adverse effects</subject><subject>Ileostomy - methods</subject><subject>Ileostomy - mortality</subject><subject>Length of Stay</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Netherlands - epidemiology</subject><subject>Original Paper</subject><subject>Rectal Neoplasms - surgery</subject><subject>Reoperation - adverse effects</subject><subject>Reoperation - methods</subject><subject>Retrospective Studies</subject><issn>0014-312X</issn><issn>1421-9921</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpt0EtLAzEUBeAgitbHwr3IQDe6GM3NY5IspfiCglIV3A2Z5o5Up5OazAj-e1OqFcRVOMl3L-EQcgj0DECac0opl4pKvkEGIBjkxjDYJANKQeQc2PMO2Y3xNUVplNkmO0wopYDqAakmGPumi5mvs5FvYxf6aTfz7TLfB99hSh-Yjb1fZLcN-tj5-QxjZluXTfADQ7RN9tCHFwyfWe1DWtL4kKZ-r_fJVm2biAff5x55urp8HN3k47vr29HFOJ8KprvcojOschxpZS2rXQFcikKoSmlXUUk1OAeCF0ZwXmhpUBZQCIZIkRmQlO-Rk9XeRfDvPcaunM_iFJvGtuj7WIJkRksOiic6_ENffR_a9LukhOBaKK2TOl2pafAxBqzLRZjNbfgsgZbL4st18ckef2_sqzm6tfxpOoGjFXizy1bWYD0__Pf58mGyEuXC1fwLomqRoA</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>Abegg, R.M.</creator><creator>Brokelman, W.</creator><creator>van Bebber, I.P.</creator><creator>Bosscha, K.</creator><creator>Prins, H.A.</creator><creator>Lips, D.J.</creator><general>S. Karger AG</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20140101</creationdate><title>Results of Construction of Protective Loop Ileostomies and Reversal Surgery for Colorectal Surgery</title><author>Abegg, R.M. ; Brokelman, W. ; van Bebber, I.P. ; Bosscha, K. ; Prins, H.A. ; Lips, D.J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c428t-aed92bd3e0baa2fd61354647b78db05081dd143694336859e561642ee0e291503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aged</topic><topic>Anastomotic Leak - etiology</topic><topic>Anastomotic Leak - prevention & control</topic><topic>Colonic Neoplasms - surgery</topic><topic>Digestive System Surgical Procedures - adverse effects</topic><topic>Digestive System Surgical Procedures - methods</topic><topic>Digestive System Surgical Procedures - mortality</topic><topic>Female</topic><topic>Humans</topic><topic>Ileostomy - adverse effects</topic><topic>Ileostomy - methods</topic><topic>Ileostomy - mortality</topic><topic>Length of Stay</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Netherlands - epidemiology</topic><topic>Original Paper</topic><topic>Rectal Neoplasms - surgery</topic><topic>Reoperation - adverse effects</topic><topic>Reoperation - methods</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Abegg, R.M.</creatorcontrib><creatorcontrib>Brokelman, W.</creatorcontrib><creatorcontrib>van Bebber, I.P.</creatorcontrib><creatorcontrib>Bosscha, K.</creatorcontrib><creatorcontrib>Prins, H.A.</creatorcontrib><creatorcontrib>Lips, D.J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>European surgical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Abegg, R.M.</au><au>Brokelman, W.</au><au>van Bebber, I.P.</au><au>Bosscha, K.</au><au>Prins, H.A.</au><au>Lips, D.J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Results of Construction of Protective Loop Ileostomies and Reversal Surgery for Colorectal Surgery</atitle><jtitle>European surgical research</jtitle><addtitle>Eur Surg Res</addtitle><date>2014-01-01</date><risdate>2014</risdate><volume>52</volume><issue>1-2</issue><spage>63</spage><epage>72</epage><pages>63-72</pages><issn>0014-312X</issn><eissn>1421-9921</eissn><abstract>Background: Protective loop ileostomies in colorectal surgery are constructed to reduce morbidity and reinterventions related to the primary operation. However, ileostomies are associated with stoma-related morbidity and postoperative complications following reversal surgery. Dutch national data show increased use of loop ileostomies in colorectal surgery for cancer justifying an adequate assessment of its morbidity. This study was undertaken to investigate morbidity associated with protective loop ileostomies in colorectal surgery. Methods: Retrospectively, 118 consecutive patients undergoing left-sided colonic or rectal resection with protective loop ileostomy were included. Primary outcome was 30-day mortality. Secondary endpoints included total complication rate (including stoma-related morbidity), total reintervention risk, anastomotic leakage risk and total length of stay. Results: No mortality was observed. Overall major complication, reintervention and anastomotic leakage risk for colorectal surgery were 20, 20 and 3.9%, respectively. Combined length of stay for stoma-related morbidity and reversal surgery was 12.7 days. The risk for stoma-related morbidity was 35%, and the risk for nonelective reversal was 12%. Closure rate (mean follow-up of 15 months) was 87% with a mean interval of 125 days. Reversal surgery was not correlated with mortality but with major complications (11%) and reintervention risk, anastomotic leakage risk (3.8%) and a mean length of stay of 9 days. Conclusion: Construction of loop ileostomies in left-sided colonic or rectal resection is associated with a low risk for anastomotic leakage at the expense of substantial stoma-related morbidity and morbidity related to reversal surgery. More accurate identification of colorectal cancer patients benefitting from protective loop ileostomy seems to be warranted.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>24777108</pmid><doi>10.1159/000357053</doi><tpages>10</tpages></addata></record> |
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subjects | Aged Anastomotic Leak - etiology Anastomotic Leak - prevention & control Colonic Neoplasms - surgery Digestive System Surgical Procedures - adverse effects Digestive System Surgical Procedures - methods Digestive System Surgical Procedures - mortality Female Humans Ileostomy - adverse effects Ileostomy - methods Ileostomy - mortality Length of Stay Male Middle Aged Netherlands - epidemiology Original Paper Rectal Neoplasms - surgery Reoperation - adverse effects Reoperation - methods Retrospective Studies |
title | Results of Construction of Protective Loop Ileostomies and Reversal Surgery for Colorectal Surgery |
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