Chronic Kidney Disease Causes Disruption of Gastric and Small Intestinal Epithelial Tight Junction

Background: Integrity of the tight junction (TJ) which seals the gap between the epithelial cells of the gastrointestinal tract is critical in preventing the entry of the microbial toxins, antigens, and other harmful products in the subepithelial tissues and the internal milieu. By enabling the abso...

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Veröffentlicht in:	American journal of nephrology 2013-01, Vol.38 (2), p.99-103
Hauptverfasser:	Vaziri, Nosratola D., Yuan, Jun, Nazertehrani, Sohrab, Ni, Zhenmin, Liu, Shuman
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Pressure Body Weight Claudin-1 - metabolism Epithelial Cells - pathology Inflammation Intestine, Small - physiopathology Kidney Failure, Chronic - physiopathology Male Occludin - metabolism Original Report: Laboratory Investigation Oxidative Stress Rats Rats, Sprague-Dawley Stomach - physiopathology Tight Junction Proteins - metabolism Tight Junctions - pathology Zonula Occludens-1 Protein - metabolism
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