Lisinopril Protects Against the Adriamycin Nephropathy and Reverses the Renalase Reduction: Potential Role of Renalase in Adriamycin Nephropathy

Aims: To investigate the potential role of renalase in adriamycin nephropathy and the effect of lisinopril on the regulation of renalase. Methods: Adriamycin nephropathy was induced in male Wistar rats (n=12) by a single injection of adriamycin at 2 mg/kg body weight. Rats were then randomly assigne...

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Veröffentlicht in:	Kidney & blood pressure research 2013-01, Vol.37 (4-5), p.295-304
Hauptverfasser:	Han, Pengxun, Sun, Huili, Xu, Yuanzhao, Zeng, Youjia, Yi, Wuyong, Wu, Jia, Shao, Mumin, Li, Shunmin, Yi, Tiegang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adriamycin nephropathy Angiotensin-Converting Enzyme Inhibitors - therapeutic use Animals Blood pressure Doxorubicin - toxicity Kidney Diseases - chemically induced Kidney Diseases - enzymology Kidney Diseases - prevention & control Lisinopril Lisinopril - therapeutic use Male Monoamine Oxidase - metabolism Original Paper Rats Rats, Wistar Renalase
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