Thymic Stromal Lymphopoietin: A Promising Therapeutic Target for Allergic Diseases

Thymic stromal lymphopoietin (TSLP), an interleukin 7-like cytokine, can trigger dendritic cell (DC)-mediated T-helper type 2 (Th2) inflammatory responses. Recent evidence demonstrates that cytokines TSLP and OX40 (CD134)/OX40 ligand seem to be important players in the maintenance of Th2 memory pool...

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Veröffentlicht in:	International archives of allergy and immunology 2013-01, Vol.160 (1), p.18-26
Hauptverfasser:	Wang, W.L., Li, H.Y., Zhang, M.S., Gao, P.S., He, S.H., Zheng, T., Zhu, Z., Zhou, L.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Animals Asthma Asthma - immunology Asthma - metabolism Asthma - therapy Cytokines Cytokines - genetics Cytokines - immunology Cytokines - metabolism Dendritic Cells - immunology Humans Hypersensitivity - immunology Hypersensitivity - metabolism Hypersensitivity - therapy Inflammation - immunology Inflammation Mediators - immunology OX40 Ligand - immunology OX40 Ligand - metabolism Pathogenesis Review T cell receptors Th2 Cells - immunology
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