Inhibition of Irritation and Contact Hypersensitivity by Ethacrynic Acid

The immunosuppressive effect of topical ethacrynic acid (ECA) was tested on both the induction and elicitation phases of contact sensitization in a mouse model. ECA (0.5% in vehicle) reduced the sensitization response by >50% when the sensitizer was either dinitrochlorobenzene (DNCB), oxazalone (...

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Veröffentlicht in:Skin pharmacology and applied skin physiology 1998, Vol.11 (4-5), p.279-288
Hauptverfasser: Wille, John J., Kydonieus, Agis F., Kalish, Richard S.
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Sprache:eng
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