Reduced Expression of Cyclin-Dependent Kinase Inhibitor p27Kip1 in Oral Malignant Tumors

p27 Kip1 , a cyclin-dependent kinase (CDK) inhibitor, blocks progression from the G 1 to S phase by binding cyclin E-CDK2 and inhibiting their activities. We studied the expression of p27 in oral tumors by immunohistochemistry to determine whether lack of p27 plays a role in the development and prog...

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Veröffentlicht in:Pathobiology (Basel) 1999, Vol.67 (4), p.169-173
Hauptverfasser: Ito, Reiko, Yasui, Wataru, Ogawa, Yuzo, Toyosawa, Satoru, Tahara, Eiichi, Ijuhin, Naokuni
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Sprache:eng
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