Role of IL-23-Th17 Cell Axis in Allergic Airway Inflammation

Asthma is characterized by chronic airway inflammation with intense eosinophil and lymphocyte infiltration, mucus hyperproduction, and airway hyperresponsiveness to a variety of stimuli. It is now generally accepted that antigen-specific Th2 cells and their cytokines orchestrate these pathognomonic...

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Veröffentlicht in:	International archives of allergy and immunology 2009-01, Vol.149 (Suppl 1), p.108-112
Hauptverfasser:	Wakashin, Hidefumi, Hirose, Koichi, Iwamoto, Itsuo, Nakajima, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asthma Asthma - immunology Biological and medical sciences Cellular biology Chronic obstructive pulmonary disease, asthma Cytokines Eosinophils - immunology Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunopathology Inflammation - immunology Interleukin-17 - metabolism Interleukin-23 - metabolism Leukocytes Lymphocytes Medical sciences Mini Review Neutrophils - immunology Pneumology Rodents Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis T-Lymphocyte Subsets - immunology T-Lymphocytes, Helper-Inducer - immunology
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