Intrathecal Administration of Thrombin Inhibitor Ameliorates Cerebral Vasospasm

The role of thrombin as a spasmogen after subarachnoid hemorrhage was evaluated using the intrathecally administered thrombin inhibitor hirudin, released from a drug delivery system (DDS) based on collagen in a canine vasospasm model. The DDS was implanted into the cisterna magna with autologous blo...

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Veröffentlicht in:	Cerebrovascular diseases (Basel, Switzerland) Switzerland), 2000, Vol.10 (6), p.424-430
Hauptverfasser:	Kudo, Akira, Suzuki, Michiyasu, Kubo, Yoshitaka, Watanabe, Mikio, Yoshida, Kenji, Doi, Mamoru, Kuroda, Kiyoshi, Ogawa, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Original Paper
Online-Zugang:	Volltext
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