Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: The GENEVA Study

Recent reports of a potentially increased risk of amyotrophic lateral sclerosis (ALS) for veterans deployed to the 1990–1991 Persian Gulf War prompted the Department of Veterans Affairs to establish a National Registry of Veterans with ALS, charged with the goal of enrolling all US veterans with a n...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Neuroepidemiology 2008-01, Vol.30 (3), p.191-204
Hauptverfasser: Schmidt, Silke, Allen, Kelli D., Loiacono, Valerie T., Norman, Barbara, Stanwyck, Catherine L., Nord, Kristina M., Williams, Christina D., Kasarskis, Edward J., Kamel, Freya, McGuire, Valerie, Nelson, Lorene M., Oddone, Eugene Z.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 204
container_issue 3
container_start_page 191
container_title Neuroepidemiology
container_volume 30
creator Schmidt, Silke
Allen, Kelli D.
Loiacono, Valerie T.
Norman, Barbara
Stanwyck, Catherine L.
Nord, Kristina M.
Williams, Christina D.
Kasarskis, Edward J.
Kamel, Freya
McGuire, Valerie
Nelson, Lorene M.
Oddone, Eugene Z.
description Recent reports of a potentially increased risk of amyotrophic lateral sclerosis (ALS) for veterans deployed to the 1990–1991 Persian Gulf War prompted the Department of Veterans Affairs to establish a National Registry of Veterans with ALS, charged with the goal of enrolling all US veterans with a neurologist-confirmed diagnosis of ALS. The Genes and Environmental Exposures in Veterans with ALS study (GENEVA) is a case-control study presently enrolling cases from the Department of Veterans Affairs registry and a representative sample of veteran controls to evaluate the joint contributions of genetic susceptibility and environmental exposures to the risk of sporadic ALS. The GENEVA study design, recruitment strategies, methods of collecting DNA samples and environmental risk factor information are described here, along with a summary of demographic characteristics of the participants (537 cases, 292 controls) enrolled to date.
doi_str_mv 10.1159/000126911
format Article
fullrecord <record><control><sourceid>karger_cross</sourceid><recordid>TN_cdi_karger_primary_126911</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>126911</sourcerecordid><originalsourceid>FETCH-LOGICAL-c215t-dc5a0aaca10e6e23b2025cce5e562e50c48df6a91949d47f919032e4308ff4e83</originalsourceid><addsrcrecordid>eNpFkDFPwzAQhS0EoqUwsDN4ZQjcOXaI2aoqFKQKhpauketcaCB1KjsF8u9JVQTTnfR9enp6jF0i3CAqfQsAKBKNeMSGKEUcgYD0mA1BKIxUrGDAzkJ47y2lU33KBphKgQL1kK2m5Chw4wqeuc_KN25DrjU1z763Tdj5nlWOL6klb1zgX1W75uNN17S-2a4ry2dmT2o-tzX5JlThni_WxKfZc7Yc83m7K7pzdlKaOtDF7x2x14dsMXmMZi_Tp8l4FlmBqo0KqwwYYw0CJSTilejrW0uKVCJIgZVpUSZGo5a6kHdl_0AsSMaQlqWkNB6x60Ou7YsET2W-9dXG-C5HyPc75X879e7Vwf0w_o38v3nAP81UYd4</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: The GENEVA Study</title><source>Karger Journals</source><source>Alma/SFX Local Collection</source><creator>Schmidt, Silke ; Allen, Kelli D. ; Loiacono, Valerie T. ; Norman, Barbara ; Stanwyck, Catherine L. ; Nord, Kristina M. ; Williams, Christina D. ; Kasarskis, Edward J. ; Kamel, Freya ; McGuire, Valerie ; Nelson, Lorene M. ; Oddone, Eugene Z.</creator><creatorcontrib>Schmidt, Silke ; Allen, Kelli D. ; Loiacono, Valerie T. ; Norman, Barbara ; Stanwyck, Catherine L. ; Nord, Kristina M. ; Williams, Christina D. ; Kasarskis, Edward J. ; Kamel, Freya ; McGuire, Valerie ; Nelson, Lorene M. ; Oddone, Eugene Z.</creatorcontrib><description>Recent reports of a potentially increased risk of amyotrophic lateral sclerosis (ALS) for veterans deployed to the 1990–1991 Persian Gulf War prompted the Department of Veterans Affairs to establish a National Registry of Veterans with ALS, charged with the goal of enrolling all US veterans with a neurologist-confirmed diagnosis of ALS. The Genes and Environmental Exposures in Veterans with ALS study (GENEVA) is a case-control study presently enrolling cases from the Department of Veterans Affairs registry and a representative sample of veteran controls to evaluate the joint contributions of genetic susceptibility and environmental exposures to the risk of sporadic ALS. The GENEVA study design, recruitment strategies, methods of collecting DNA samples and environmental risk factor information are described here, along with a summary of demographic characteristics of the participants (537 cases, 292 controls) enrolled to date.</description><identifier>ISSN: 0251-5350</identifier><identifier>EISSN: 1423-0208</identifier><identifier>DOI: 10.1159/000126911</identifier><identifier>PMID: 18421219</identifier><language>eng</language><publisher>Basel, Switzerland</publisher><subject>Methods in Neuroepidemiology</subject><ispartof>Neuroepidemiology, 2008-01, Vol.30 (3), p.191-204</ispartof><rights>2008 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c215t-dc5a0aaca10e6e23b2025cce5e562e50c48df6a91949d47f919032e4308ff4e83</citedby><cites>FETCH-LOGICAL-c215t-dc5a0aaca10e6e23b2025cce5e562e50c48df6a91949d47f919032e4308ff4e83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,2425,27907,27908</link.rule.ids></links><search><creatorcontrib>Schmidt, Silke</creatorcontrib><creatorcontrib>Allen, Kelli D.</creatorcontrib><creatorcontrib>Loiacono, Valerie T.</creatorcontrib><creatorcontrib>Norman, Barbara</creatorcontrib><creatorcontrib>Stanwyck, Catherine L.</creatorcontrib><creatorcontrib>Nord, Kristina M.</creatorcontrib><creatorcontrib>Williams, Christina D.</creatorcontrib><creatorcontrib>Kasarskis, Edward J.</creatorcontrib><creatorcontrib>Kamel, Freya</creatorcontrib><creatorcontrib>McGuire, Valerie</creatorcontrib><creatorcontrib>Nelson, Lorene M.</creatorcontrib><creatorcontrib>Oddone, Eugene Z.</creatorcontrib><title>Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: The GENEVA Study</title><title>Neuroepidemiology</title><addtitle>Neuroepidemiology</addtitle><description>Recent reports of a potentially increased risk of amyotrophic lateral sclerosis (ALS) for veterans deployed to the 1990–1991 Persian Gulf War prompted the Department of Veterans Affairs to establish a National Registry of Veterans with ALS, charged with the goal of enrolling all US veterans with a neurologist-confirmed diagnosis of ALS. The Genes and Environmental Exposures in Veterans with ALS study (GENEVA) is a case-control study presently enrolling cases from the Department of Veterans Affairs registry and a representative sample of veteran controls to evaluate the joint contributions of genetic susceptibility and environmental exposures to the risk of sporadic ALS. The GENEVA study design, recruitment strategies, methods of collecting DNA samples and environmental risk factor information are described here, along with a summary of demographic characteristics of the participants (537 cases, 292 controls) enrolled to date.</description><subject>Methods in Neuroepidemiology</subject><issn>0251-5350</issn><issn>1423-0208</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNpFkDFPwzAQhS0EoqUwsDN4ZQjcOXaI2aoqFKQKhpauketcaCB1KjsF8u9JVQTTnfR9enp6jF0i3CAqfQsAKBKNeMSGKEUcgYD0mA1BKIxUrGDAzkJ47y2lU33KBphKgQL1kK2m5Chw4wqeuc_KN25DrjU1z763Tdj5nlWOL6klb1zgX1W75uNN17S-2a4ry2dmT2o-tzX5JlThni_WxKfZc7Yc83m7K7pzdlKaOtDF7x2x14dsMXmMZi_Tp8l4FlmBqo0KqwwYYw0CJSTilejrW0uKVCJIgZVpUSZGo5a6kHdl_0AsSMaQlqWkNB6x60Ou7YsET2W-9dXG-C5HyPc75X879e7Vwf0w_o38v3nAP81UYd4</recordid><startdate>20080101</startdate><enddate>20080101</enddate><creator>Schmidt, Silke</creator><creator>Allen, Kelli D.</creator><creator>Loiacono, Valerie T.</creator><creator>Norman, Barbara</creator><creator>Stanwyck, Catherine L.</creator><creator>Nord, Kristina M.</creator><creator>Williams, Christina D.</creator><creator>Kasarskis, Edward J.</creator><creator>Kamel, Freya</creator><creator>McGuire, Valerie</creator><creator>Nelson, Lorene M.</creator><creator>Oddone, Eugene Z.</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20080101</creationdate><title>Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: The GENEVA Study</title><author>Schmidt, Silke ; Allen, Kelli D. ; Loiacono, Valerie T. ; Norman, Barbara ; Stanwyck, Catherine L. ; Nord, Kristina M. ; Williams, Christina D. ; Kasarskis, Edward J. ; Kamel, Freya ; McGuire, Valerie ; Nelson, Lorene M. ; Oddone, Eugene Z.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c215t-dc5a0aaca10e6e23b2025cce5e562e50c48df6a91949d47f919032e4308ff4e83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Methods in Neuroepidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schmidt, Silke</creatorcontrib><creatorcontrib>Allen, Kelli D.</creatorcontrib><creatorcontrib>Loiacono, Valerie T.</creatorcontrib><creatorcontrib>Norman, Barbara</creatorcontrib><creatorcontrib>Stanwyck, Catherine L.</creatorcontrib><creatorcontrib>Nord, Kristina M.</creatorcontrib><creatorcontrib>Williams, Christina D.</creatorcontrib><creatorcontrib>Kasarskis, Edward J.</creatorcontrib><creatorcontrib>Kamel, Freya</creatorcontrib><creatorcontrib>McGuire, Valerie</creatorcontrib><creatorcontrib>Nelson, Lorene M.</creatorcontrib><creatorcontrib>Oddone, Eugene Z.</creatorcontrib><collection>CrossRef</collection><jtitle>Neuroepidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schmidt, Silke</au><au>Allen, Kelli D.</au><au>Loiacono, Valerie T.</au><au>Norman, Barbara</au><au>Stanwyck, Catherine L.</au><au>Nord, Kristina M.</au><au>Williams, Christina D.</au><au>Kasarskis, Edward J.</au><au>Kamel, Freya</au><au>McGuire, Valerie</au><au>Nelson, Lorene M.</au><au>Oddone, Eugene Z.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: The GENEVA Study</atitle><jtitle>Neuroepidemiology</jtitle><addtitle>Neuroepidemiology</addtitle><date>2008-01-01</date><risdate>2008</risdate><volume>30</volume><issue>3</issue><spage>191</spage><epage>204</epage><pages>191-204</pages><issn>0251-5350</issn><eissn>1423-0208</eissn><abstract>Recent reports of a potentially increased risk of amyotrophic lateral sclerosis (ALS) for veterans deployed to the 1990–1991 Persian Gulf War prompted the Department of Veterans Affairs to establish a National Registry of Veterans with ALS, charged with the goal of enrolling all US veterans with a neurologist-confirmed diagnosis of ALS. The Genes and Environmental Exposures in Veterans with ALS study (GENEVA) is a case-control study presently enrolling cases from the Department of Veterans Affairs registry and a representative sample of veteran controls to evaluate the joint contributions of genetic susceptibility and environmental exposures to the risk of sporadic ALS. The GENEVA study design, recruitment strategies, methods of collecting DNA samples and environmental risk factor information are described here, along with a summary of demographic characteristics of the participants (537 cases, 292 controls) enrolled to date.</abstract><cop>Basel, Switzerland</cop><pmid>18421219</pmid><doi>10.1159/000126911</doi><tpages>14</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0251-5350
ispartof Neuroepidemiology, 2008-01, Vol.30 (3), p.191-204
issn 0251-5350
1423-0208
language eng
recordid cdi_karger_primary_126911
source Karger Journals; Alma/SFX Local Collection
subjects Methods in Neuroepidemiology
title Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: The GENEVA Study
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T18%3A02%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-karger_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Genes%20and%20Environmental%20Exposures%20in%20Veterans%20with%20Amyotrophic%20Lateral%20Sclerosis:%20The%20GENEVA%20Study&rft.jtitle=Neuroepidemiology&rft.au=Schmidt,%20Silke&rft.date=2008-01-01&rft.volume=30&rft.issue=3&rft.spage=191&rft.epage=204&rft.pages=191-204&rft.issn=0251-5350&rft.eissn=1423-0208&rft_id=info:doi/10.1159/000126911&rft_dat=%3Ckarger_cross%3E126911%3C/karger_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/18421219&rfr_iscdi=true