Genome-Wide Profiling of Antigen-Induced Time Course Expression Using Murine Models for Acute and Chronic Asthma

Background: Asthma is a complex-trait disease caused by complicated interactions among multiple genetic and environmental risk factors. The clinical symptoms of asthma, such as periodic airway obstruction, hyperresponsiveness and mucus hypersecretion, are mediated by acute and chronic bronchial infl...

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Veröffentlicht in:	International archives of allergy and immunology 2008-01, Vol.146 (1), p.44-56
Hauptverfasser:	Park, Seong Gyu, Choi, Jung-Won, Kim, Hyun jae, Roh, Gu Seob, Bok, Jeong, Go, Min Jin, Kwack, KyuBum, Oh, Bermseok, Kim, Yeonjung
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Animals Asthma Asthma - genetics Asthma - immunology Biological and medical sciences Disease Models, Animal Female Fundamental and applied biological sciences. Psychology Fundamental immunology Gene expression Gene Expression Profiling - methods Genomics Genomics - methods Histocytochemistry Immunoglobulin E - blood Immunopathology Lung - immunology Medical sciences Mice Mice, Inbred BALB C Oligonucleotide Array Sequence Analysis Original Paper Ovalbumin - immunology Ovalbumin - pharmacology Reverse Transcriptase Polymerase Chain Reaction Risk factors RNA, Messenger - biosynthesis RNA, Messenger - genetics Rodents Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Th2 Cells - immunology Transcription, Genetic Up-Regulation
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