Pharmacodynamic Study of the Saltz Regimen for Metastatic Colorectal Cancer in a Hemodialyzed Patient

Objective: Combination therapy with irinotecan (CPT-11), 5-fluorouracil (5-FU) and leucovorin is widely used for the treatment of metastatic colorectal cancer. However, little is known about the safety of chemotherapy of malignancies in hemodialysis (HD) patients. We encountered a patient with color...

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Veröffentlicht in:	Chemotherapy (Basel) 2007-01, Vol.53 (6), p.418-421
Hauptverfasser:	Akiyama, Shinichiro, Nakayama, Hidetsugu, Takami, Hiroya, Gotoh, Hiromichi, Gotoh, Yoshikazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic Combined Chemotherapy Protocols - pharmacology Camptothecin - administration & dosage Camptothecin - analogs & derivatives Case studies Chemotherapy Colorectal cancer Colorectal Neoplasms - drug therapy Colorectal Neoplasms - etiology Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - drug therapy Diabetes Mellitus, Type 1 - surgery Drug therapy Fluorouracil - administration & dosage Hemodialysis Humans Kinetics Leucovorin - administration & dosage Male Pharmacology Renal Dialysis Treatment Outcome
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