Fungal Thigmotropism in Onychomycosis and in a Clear Hydrogel Pad Model
Background: Thigmotropism is a biological characteristic corresponding to the directional growth of cells following topographical guidance cues. This behavior has been shown experimentally with fungal hyphae of both dermatophytes and nondermatophyte molds, as well as with the mycelial phase of the d...
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| Veröffentlicht in: | Dermatology (Basel) 2007-01, Vol.215 (2), p.107-113 |
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| creator | Piérard, G.E. Piérard-Franchimont, C. Quatresooz, P. |
| description | Background: Thigmotropism is a biological characteristic corresponding to the directional growth of cells following topographical guidance cues. This behavior has been shown experimentally with fungal hyphae of both dermatophytes and nondermatophyte molds, as well as with the mycelial phase of the dimorphic yeast Candida albicans. Objective and Methods: We presently document this phenomenon using histomycology in onychomycoses of various fungal origins. Results: This mechanism is involved in the invasive phase of the pathogen or opportunistic fungi, and it probably governs various clinical aspects of onychomycoses. We incidentally disclosed fungal invasions of hydrogel pads. Conclusion: Thigmotropism can in part explain the diversity of orientations and shapes of fungi invading nail plates. The same phenomenon was disclosed inside hydrogel pads. As this material is transparent and easy to cut for microscopic examination, fungal thigmotropism is conveniently explored by this way. |
| doi_str_mv | 10.1159/000104260 |
| format | Article |
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This behavior has been shown experimentally with fungal hyphae of both dermatophytes and nondermatophyte molds, as well as with the mycelial phase of the dimorphic yeast Candida albicans. Objective and Methods: We presently document this phenomenon using histomycology in onychomycoses of various fungal origins. Results: This mechanism is involved in the invasive phase of the pathogen or opportunistic fungi, and it probably governs various clinical aspects of onychomycoses. We incidentally disclosed fungal invasions of hydrogel pads. Conclusion: Thigmotropism can in part explain the diversity of orientations and shapes of fungi invading nail plates. The same phenomenon was disclosed inside hydrogel pads. As this material is transparent and easy to cut for microscopic examination, fungal thigmotropism is conveniently explored by this way.</description><identifier>ISSN: 1018-8665</identifier><identifier>ISSN: 1421-9832</identifier><identifier>EISSN: 1421-9832</identifier><identifier>DOI: 10.1159/000104260</identifier><identifier>PMID: 17684371</identifier><language>eng</language><publisher>Basel, Switzerland: Karger</publisher><subject><![CDATA[Arthrodermataceae - growth & development ; Arthrodermataceae - isolation & purification ; Arthrodermataceae/growth & development/isolation & purification ; Aspergillus - growth & development ; Aspergillus - isolation & purification ; Aspergillus/growth & development/isolation & purification ; Biological and medical sciences ; Candida albicans ; Candida albicans - growth & development ; Candida albicans - isolation & purification ; Candida albicans/growth & development/isolation & purification ; Cellular biology ; Clinical and Laboratory Investigations ; Dermatologie ; Dermatology ; Fungal infections ; Fusarium - growth & development ; Fusarium - isolation & purification ; Fusarium/growth & development/isolation & purification ; Human health sciences ; Human mycoses ; Humans ; Hydrogel ; Hydrogel, Polyethylene Glycol Dimethacrylate ; Infectious diseases ; Medical sciences ; Microscopy, Polarization ; Mitosporic Fungi - growth & development ; Mitosporic Fungi - isolation & purification ; Mitosporic Fungi/growth & development/isolation & purification ; Mycoses ; Mycoses of the skin ; Nails - microbiology ; Nails - pathology ; Nails/microbiology/pathology ; Onychomycosis - microbiology ; Onychomycosis - pathology ; Onychomycosis/microbiology/pathology ; Sciences de la santé humaine ; Skin diseases ; Tropism - physiology]]></subject><ispartof>Dermatology (Basel), 2007-01, Vol.215 (2), p.107-113</ispartof><rights>2007 S. Karger AG, Basel</rights><rights>2007 INIST-CNRS</rights><rights>Copyright (c) 2007 S. Karger AG, Basel.</rights><rights>Copyright (c) 2007 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c434t-ebb324ce541648439c50bed16bb5a211da072acd3632ebacddfed5b8d659bee23</citedby><cites>FETCH-LOGICAL-c434t-ebb324ce541648439c50bed16bb5a211da072acd3632ebacddfed5b8d659bee23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,2423,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18953937$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17684371$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Piérard, G.E.</creatorcontrib><creatorcontrib>Piérard-Franchimont, C.</creatorcontrib><creatorcontrib>Quatresooz, P.</creatorcontrib><title>Fungal Thigmotropism in Onychomycosis and in a Clear Hydrogel Pad Model</title><title>Dermatology (Basel)</title><addtitle>Dermatology</addtitle><description>Background: Thigmotropism is a biological characteristic corresponding to the directional growth of cells following topographical guidance cues. This behavior has been shown experimentally with fungal hyphae of both dermatophytes and nondermatophyte molds, as well as with the mycelial phase of the dimorphic yeast Candida albicans. Objective and Methods: We presently document this phenomenon using histomycology in onychomycoses of various fungal origins. Results: This mechanism is involved in the invasive phase of the pathogen or opportunistic fungi, and it probably governs various clinical aspects of onychomycoses. We incidentally disclosed fungal invasions of hydrogel pads. Conclusion: Thigmotropism can in part explain the diversity of orientations and shapes of fungi invading nail plates. The same phenomenon was disclosed inside hydrogel pads. As this material is transparent and easy to cut for microscopic examination, fungal thigmotropism is conveniently explored by this way.</description><subject>Arthrodermataceae - growth & development</subject><subject>Arthrodermataceae - isolation & purification</subject><subject>Arthrodermataceae/growth & development/isolation & purification</subject><subject>Aspergillus - growth & development</subject><subject>Aspergillus - isolation & purification</subject><subject>Aspergillus/growth & development/isolation & purification</subject><subject>Biological and medical sciences</subject><subject>Candida albicans</subject><subject>Candida albicans - growth & development</subject><subject>Candida albicans - isolation & purification</subject><subject>Candida albicans/growth & development/isolation & purification</subject><subject>Cellular biology</subject><subject>Clinical and Laboratory Investigations</subject><subject>Dermatologie</subject><subject>Dermatology</subject><subject>Fungal infections</subject><subject>Fusarium - growth & development</subject><subject>Fusarium - isolation & purification</subject><subject>Fusarium/growth & development/isolation & purification</subject><subject>Human health sciences</subject><subject>Human mycoses</subject><subject>Humans</subject><subject>Hydrogel</subject><subject>Hydrogel, Polyethylene Glycol Dimethacrylate</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Microscopy, Polarization</subject><subject>Mitosporic Fungi - growth & development</subject><subject>Mitosporic Fungi - isolation & purification</subject><subject>Mitosporic Fungi/growth & development/isolation & purification</subject><subject>Mycoses</subject><subject>Mycoses of the skin</subject><subject>Nails - microbiology</subject><subject>Nails - pathology</subject><subject>Nails/microbiology/pathology</subject><subject>Onychomycosis - microbiology</subject><subject>Onychomycosis - pathology</subject><subject>Onychomycosis/microbiology/pathology</subject><subject>Sciences de la santé humaine</subject><subject>Skin diseases</subject><subject>Tropism - physiology</subject><issn>1018-8665</issn><issn>1421-9832</issn><issn>1421-9832</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqF0c1rFDEUAPAgiq3Vg3eRQVDwMJrvmRzLYluhpT3Uc8jH22lqZrImO8L-9806i5VePOURfu-Lh9Bbgr8QItRXjDHBnEr8DB0TTkmrekaf1xiTvu2lFEfoVSn3ldG-Uy_REelkz1lHjtH52TwNJja3d2EY0zanTShjE6bmetq5uzTuXCqhNGby-0_TrCKY3FzsfE4DxObG-OYqeYiv0Yu1iQXeHN4T9OPs2-3qor28Pv--Or1sHWd824K1jHIHghPJ6wjKCWzBE2mtMJQQb3BHjfNMMgq2Bn4NXtjeS6EsAGUniCx1Y4ABdMo26N9UJxOWeI6DNk5b0JTKXotOqprzacnZ5PRrhrLVYygOYjQTpLlo2ROmmPg_pFhhLmhX4Ycn8D7NeaqLa9oJTCSWe_R5QS6nUjKs9SaH0eSdJljv76b_3q3a94eCsx3BP8rDoSr4eACmOBPX2UwulEfXK1F32Dd9t7ifJg-Q_2n5p88DaB-mwA</recordid><startdate>20070101</startdate><enddate>20070101</enddate><creator>Piérard, G.E.</creator><creator>Piérard-Franchimont, C.</creator><creator>Quatresooz, P.</creator><general>Karger</general><general>S. 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growth & development</topic><topic>Mitosporic Fungi - isolation & purification</topic><topic>Mitosporic Fungi/growth & development/isolation & purification</topic><topic>Mycoses</topic><topic>Mycoses of the skin</topic><topic>Nails - microbiology</topic><topic>Nails - pathology</topic><topic>Nails/microbiology/pathology</topic><topic>Onychomycosis - microbiology</topic><topic>Onychomycosis - pathology</topic><topic>Onychomycosis/microbiology/pathology</topic><topic>Sciences de la santé humaine</topic><topic>Skin diseases</topic><topic>Tropism - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Piérard, G.E.</creatorcontrib><creatorcontrib>Piérard-Franchimont, C.</creatorcontrib><creatorcontrib>Quatresooz, P.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><collection>Université de Liège - Open Repository and Bibliography (ORBI)</collection><jtitle>Dermatology (Basel)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Piérard, G.E.</au><au>Piérard-Franchimont, C.</au><au>Quatresooz, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fungal Thigmotropism in Onychomycosis and in a Clear Hydrogel Pad Model</atitle><jtitle>Dermatology (Basel)</jtitle><addtitle>Dermatology</addtitle><date>2007-01-01</date><risdate>2007</risdate><volume>215</volume><issue>2</issue><spage>107</spage><epage>113</epage><pages>107-113</pages><issn>1018-8665</issn><issn>1421-9832</issn><eissn>1421-9832</eissn><abstract>Background: Thigmotropism is a biological characteristic corresponding to the directional growth of cells following topographical guidance cues. This behavior has been shown experimentally with fungal hyphae of both dermatophytes and nondermatophyte molds, as well as with the mycelial phase of the dimorphic yeast Candida albicans. Objective and Methods: We presently document this phenomenon using histomycology in onychomycoses of various fungal origins. Results: This mechanism is involved in the invasive phase of the pathogen or opportunistic fungi, and it probably governs various clinical aspects of onychomycoses. We incidentally disclosed fungal invasions of hydrogel pads. Conclusion: Thigmotropism can in part explain the diversity of orientations and shapes of fungi invading nail plates. The same phenomenon was disclosed inside hydrogel pads. As this material is transparent and easy to cut for microscopic examination, fungal thigmotropism is conveniently explored by this way.</abstract><cop>Basel, Switzerland</cop><pub>Karger</pub><pmid>17684371</pmid><doi>10.1159/000104260</doi><tpages>7</tpages></addata></record> |
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| identifier | ISSN: 1018-8665 |
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| source | Karger Journals; MEDLINE |
| subjects | Arthrodermataceae - growth & development Arthrodermataceae - isolation & purification Arthrodermataceae/growth & development/isolation & purification Aspergillus - growth & development Aspergillus - isolation & purification Aspergillus/growth & development/isolation & purification Biological and medical sciences Candida albicans Candida albicans - growth & development Candida albicans - isolation & purification Candida albicans/growth & development/isolation & purification Cellular biology Clinical and Laboratory Investigations Dermatologie Dermatology Fungal infections Fusarium - growth & development Fusarium - isolation & purification Fusarium/growth & development/isolation & purification Human health sciences Human mycoses Humans Hydrogel Hydrogel, Polyethylene Glycol Dimethacrylate Infectious diseases Medical sciences Microscopy, Polarization Mitosporic Fungi - growth & development Mitosporic Fungi - isolation & purification Mitosporic Fungi/growth & development/isolation & purification Mycoses Mycoses of the skin Nails - microbiology Nails - pathology Nails/microbiology/pathology Onychomycosis - microbiology Onychomycosis - pathology Onychomycosis/microbiology/pathology Sciences de la santé humaine Skin diseases Tropism - physiology |
| title | Fungal Thigmotropism in Onychomycosis and in a Clear Hydrogel Pad Model |
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