In utero Androgen Excess: A Developmental Commonality Preceding Polycystic Ovary Syndrome?

In utero androgen excess reliably induces polycystic ovary syndrome (PCOS)-like reproductive and metabolic traits in female monkeys, sheep, rats, and mice. In humans, however, substantial technical and ethical constraints on fetal sampling have curtailed safe, pathogenic exploration during gestation...

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Bibliographische Detailangaben

Hauptverfasser:	Abbott, David H., Kraynak, Marissa, Dumesic, Daniel A., Levine, Jon E.
Format:	Buchkapitel
Sprache:	eng
Schlagworte:	Androgens - metabolism Animals Chapter Female Humans Hyperandrogenism - etiology Hyperandrogenism - genetics Hyperandrogenism - metabolism Polycystic Ovary Syndrome - etiology Polycystic Ovary Syndrome - genetics Polycystic Ovary Syndrome - metabolism Pregnancy Prenatal Exposure Delayed Effects - etiology Prenatal Exposure Delayed Effects - genetics Prenatal Exposure Delayed Effects - metabolism
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