Ionophore A23187- and Thrombin-Induced Platelet Aggregation: Independence from Cycloxygenase Products

Stimulation of platelets labeled with [14C]-arachidonate by ionophore A23187 or thrombin produces rapid degradation of specific membrane phospholipids. This is also reflected by the release of [14C]-arachidonate, which is immediately transformed into products of the cycloxygenase and lipoxygenase en...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1978-02, Vol.75 (2), p.818-822
Hauptverfasser: Lapetina, E. G., Chandrabose, K. A., Cuatrecasas, P.
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Sprache:eng
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