Increased Concentrations of Nonesterified Arachidonic Acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic Acid, Prostaglandin E2, and Prostaglandin F2αin Epidermis of Psoriasis

Lesional epidermis of psoriasis has a probable reduction in the cyclic AMP/cyclic GMP ratio. This altered ratio may in part be responsible for the characteristic glycogen storage, rapid cell proliferation, and reduced differentiation in lesional epidermis. The concentrations of prostaglandins E2and...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1975-12, Vol.72 (12), p.5130-5134
Hauptverfasser:	Hammarstrom, Sven, Hamberg, Mats, Samuelsson, Bengt, Duell, Elizabeth A., Stawiski, Marek, Voorhees, John J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates Chromatography Epidermal cells Epidermis Esters Ethers Fatty acids Prostaglandins Psoriasis Specimens
Online-Zugang:	Volltext
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