Avoiding Recomputation in Linkage Analysis

We describe four improvements we have implemented in a version of the genetic linkage analysis programs in the LINKAGE package: subdivision of recombination classes, better handling of loops, better coordination between the optimization and output routines, and a checkpointing facility. The unifying...

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Veröffentlicht in:	Human heredity 1994-07, Vol.44 (4), p.225-237
Hauptverfasser:	Schäffer, Alejandro A., Gupta, Sandeep K., Shriram, K., Cottingham, Robert W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Automatic Data Processing - instrumentation Automatic Data Processing - statistics & numerical data Biological and medical sciences Classical genetics, quantitative genetics, hybrids Fundamental and applied biological sciences. Psychology Genetic Linkage - genetics Genetics of eukaryotes. Biological and molecular evolution Genotype Humans Methods, theories and miscellaneous Original Paper Pedigree Recombination, Genetic Software
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