SERUM PROFILE OF MYOCARDIAL ENZYMES DURING CHRONIC EXPOSURE TO LOW LEVELS OF CARBON MONOXIDE
Carbon monoxide (CO) is one of the major sources of urban air pollution. Since exposure to CO converts hemoglobin (Hb) to carboxyhemoglobin (COHb), thereby reducing the oxygencarrying capacity of the blood and placing an additional strain upon the cardiovascular system to maintain adequate tissue ox...
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| Veröffentlicht in: | Proceedings of the Pennsylvania Academy of Science 1973-01, Vol.47, p.73-76 |
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| container_title | Proceedings of the Pennsylvania Academy of Science |
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| creator | Rosenfeld, Leonard M. DeBias, Domenic A. |
| description | Carbon monoxide (CO) is one of the major sources of urban air pollution. Since exposure to CO converts hemoglobin (Hb) to carboxyhemoglobin (COHb), thereby reducing the oxygencarrying capacity of the blood and placing an additional strain upon the cardiovascular system to maintain adequate tissue oxygenation, this present investigation was undertaken to ascertain the effects of chronic exposure (up to six months) to relatively low levels of carbon monoxide (50-150 ppm) of dogs with prior myocardial infarction. Serum profiles of enzymes of the myocardium (CPK, GOT, LDH) throughout the six-month exposure period failed to provide evidence of secondary myocardial infarction. |
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Since exposure to CO converts hemoglobin (Hb) to carboxyhemoglobin (COHb), thereby reducing the oxygencarrying capacity of the blood and placing an additional strain upon the cardiovascular system to maintain adequate tissue oxygenation, this present investigation was undertaken to ascertain the effects of chronic exposure (up to six months) to relatively low levels of carbon monoxide (50-150 ppm) of dogs with prior myocardial infarction. Serum profiles of enzymes of the myocardium (CPK, GOT, LDH) throughout the six-month exposure period failed to provide evidence of secondary myocardial infarction.</description><identifier>ISSN: 0096-9222</identifier><language>eng</language><publisher>Pennsylvania Academy of Science</publisher><subject>Air pollution ; Atmospherics ; BIOLOGY ; Carbon monoxide ; Cardiovascular system ; Cigarette smoking ; Enzymes ; Hemoglobins ; Myocardial infarction ; Oxygen</subject><ispartof>Proceedings of the Pennsylvania Academy of Science, 1973-01, Vol.47, p.73-76</ispartof><rights>Copyright 1973 The Pennsylvania Academy of Science, Inc.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/44110796$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/44110796$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,58017,58250</link.rule.ids></links><search><creatorcontrib>Rosenfeld, Leonard M.</creatorcontrib><creatorcontrib>DeBias, Domenic A.</creatorcontrib><title>SERUM PROFILE OF MYOCARDIAL ENZYMES DURING CHRONIC EXPOSURE TO LOW LEVELS OF CARBON MONOXIDE</title><title>Proceedings of the Pennsylvania Academy of Science</title><description>Carbon monoxide (CO) is one of the major sources of urban air pollution. Since exposure to CO converts hemoglobin (Hb) to carboxyhemoglobin (COHb), thereby reducing the oxygencarrying capacity of the blood and placing an additional strain upon the cardiovascular system to maintain adequate tissue oxygenation, this present investigation was undertaken to ascertain the effects of chronic exposure (up to six months) to relatively low levels of carbon monoxide (50-150 ppm) of dogs with prior myocardial infarction. Serum profiles of enzymes of the myocardium (CPK, GOT, LDH) throughout the six-month exposure period failed to provide evidence of secondary myocardial infarction.</description><subject>Air pollution</subject><subject>Atmospherics</subject><subject>BIOLOGY</subject><subject>Carbon monoxide</subject><subject>Cardiovascular system</subject><subject>Cigarette smoking</subject><subject>Enzymes</subject><subject>Hemoglobins</subject><subject>Myocardial infarction</subject><subject>Oxygen</subject><issn>0096-9222</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1973</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNqFy8EKgkAUQNFZFCTlJwTvB4TRRHNp-syBcZ6MWhqBuChIikLb9PcVtG91F5czYQbngWcFjuPMmDmOPefcXnPP9W2DHQvUVQa5pkRIBEogaygKdSxCCagOTYYFxJUWagtRqkmJCLDOqag0QkkgaQ8SdyiLr_3ADSnISFEtYlyw6bm7jifz1zlbJlhGqdWPz_vQPobLrRterevaNvcDb_XvvwEnwDYc</recordid><startdate>19730101</startdate><enddate>19730101</enddate><creator>Rosenfeld, Leonard M.</creator><creator>DeBias, Domenic A.</creator><general>Pennsylvania Academy of Science</general><scope/></search><sort><creationdate>19730101</creationdate><title>SERUM PROFILE OF MYOCARDIAL ENZYMES DURING CHRONIC EXPOSURE TO LOW LEVELS OF CARBON MONOXIDE</title><author>Rosenfeld, Leonard M. ; DeBias, Domenic A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-jstor_primary_441107963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1973</creationdate><topic>Air pollution</topic><topic>Atmospherics</topic><topic>BIOLOGY</topic><topic>Carbon monoxide</topic><topic>Cardiovascular system</topic><topic>Cigarette smoking</topic><topic>Enzymes</topic><topic>Hemoglobins</topic><topic>Myocardial infarction</topic><topic>Oxygen</topic><toplevel>online_resources</toplevel><creatorcontrib>Rosenfeld, Leonard M.</creatorcontrib><creatorcontrib>DeBias, Domenic A.</creatorcontrib><jtitle>Proceedings of the Pennsylvania Academy of Science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rosenfeld, Leonard M.</au><au>DeBias, Domenic A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>SERUM PROFILE OF MYOCARDIAL ENZYMES DURING CHRONIC EXPOSURE TO LOW LEVELS OF CARBON MONOXIDE</atitle><jtitle>Proceedings of the Pennsylvania Academy of Science</jtitle><date>1973-01-01</date><risdate>1973</risdate><volume>47</volume><spage>73</spage><epage>76</epage><pages>73-76</pages><issn>0096-9222</issn><abstract>Carbon monoxide (CO) is one of the major sources of urban air pollution. Since exposure to CO converts hemoglobin (Hb) to carboxyhemoglobin (COHb), thereby reducing the oxygencarrying capacity of the blood and placing an additional strain upon the cardiovascular system to maintain adequate tissue oxygenation, this present investigation was undertaken to ascertain the effects of chronic exposure (up to six months) to relatively low levels of carbon monoxide (50-150 ppm) of dogs with prior myocardial infarction. Serum profiles of enzymes of the myocardium (CPK, GOT, LDH) throughout the six-month exposure period failed to provide evidence of secondary myocardial infarction.</abstract><pub>Pennsylvania Academy of Science</pub></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0096-9222 |
| ispartof | Proceedings of the Pennsylvania Academy of Science, 1973-01, Vol.47, p.73-76 |
| issn | 0096-9222 |
| language | eng |
| recordid | cdi_jstor_primary_44110796 |
| source | JSTOR Archive Collection A-Z Listing |
| subjects | Air pollution Atmospherics BIOLOGY Carbon monoxide Cardiovascular system Cigarette smoking Enzymes Hemoglobins Myocardial infarction Oxygen |
| title | SERUM PROFILE OF MYOCARDIAL ENZYMES DURING CHRONIC EXPOSURE TO LOW LEVELS OF CARBON MONOXIDE |
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