Cell-to-Cell Communication Competence in Simian Virus 40-Transfected Rat Ovarian Cells Is Reduced Following Tumor Selection

A pSV3neo-transfected rat ovarian cell line (SV-GC) was developed from a primary granulosa culture (GC) to study gap junctional intercellular communication (GJIC) during Simian virus 40 (SV40) transformation. SV-GC expressed SV40 large T-antigen (T-ag), grew indefinitely in culture without luteiniza...

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Veröffentlicht in:	In Vitro Cellular & Developmental Biology - Animal 1992-06, Vol.28A (6), p.436-444
Hauptverfasser:	Lisa S. Stein, Thomas H. Welsh, Jr, Wilson, Van G., Burghardt, Robert C.
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 cells Animals Antigens, Viral, Tumor - physiology Biological and medical sciences Cell Biology Cell Communication - physiology Cell interactions, adhesion Cell lines Cell Transformation, Viral - physiology Cells, Cultured Cultured cells Developmental Biology Epithelial cells Female Fundamental and applied biological sciences. Psychology Gap junctions Granulosa cell tumors Granulosa cells Humans Intercellular Junctions - physiology Intercellular Junctions - ultrastructure Life Sciences & Biomedicine Mice Mice, Nude Microscopy, Electron Molecular and cellular biology Ovarian Neoplasms - pathology Ovarian Neoplasms - physiopathology Ovarian Neoplasms - ultrastructure Ovary - cytology Ovary - physiology Ovary - ultrastructure Rats Science & Technology Simian virus 40 - genetics Simian virus 40 - immunology Transfection - genetics Transfection - physiology Transformed cell line Tumor cell line Tumor Cells, Cultured - pathology Tumor Cells, Cultured - ultrastructure Tumors
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