A Note on the Biological Activity of Root Extracts from Pleiocarpa mutica Benth. (Apocynaceae)
Several organic solvent and aqueous extractives were prepared from dried roots of Pleiocarpa mutica Benth. obtained from the Belgium Congo. All aqueous fractions produced a drop in blood pressure when administered to laboratory rats. A moist ethyl acetate extract produced most significant hypotensiv...
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| Veröffentlicht in: | Economic botany 1961-01, Vol.15 (1), p.99-103 |
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| container_title | Economic botany |
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| creator | D. P. N. Tsao J. A. Rosecrans J. J. De Feo Youngken, H. W. |
| description | Several organic solvent and aqueous extractives were prepared from dried roots of Pleiocarpa mutica Benth. obtained from the Belgium Congo. All aqueous fractions produced a drop in blood pressure when administered to laboratory rats. A moist ethyl acetate extract produced most significant hypotensive activity. Preliminary tests indicate the presence of alkaloids in the active extracts of this species, and that the activity blocks the effect of epinephrine but is not altered by atropine. The active acetate fraction also destroyed adult and larvae stages of the nematode, Panagrellus redivivus (L.) Goody when added to test cultures. |
| doi_str_mv | 10.1007/BF02906766 |
| format | Article |
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Goody when added to test cultures.</description><subject>Acetates</subject><subject>Alkaloids</subject><subject>Atropine</subject><subject>Blood pressure</subject><subject>Dosage</subject><subject>Intravenous injections</subject><subject>Nematode larvae</subject><subject>Nematodes</subject><subject>Pharmacology</subject><subject>Solvents</subject><issn>0013-0001</issn><issn>1874-9364</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1961</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNotjD1PwzAURS0EEqGwMDO8EYYUfyW2x7RqAakChDpTOc82TZXWVWJQ8--JBMu9Z7jnEnLL6JRRqh5nS8oNLVVZnpGMaSVzI0p5TjJKmcjpmJfkqu93IylWyIx8VvAak4d4gLT1MGtiG78atC1UmJqfJg0QA3zEmGBxSp3F1EPo4h7eW99EtN3Rwv47jQbM_CFtp3BfHSMOB4ve-odrchFs2_ub_56Q9XKxnj_nq7enl3m1yneGpVxyFVyJ2nGsae2pqq0LXhu0qIMqpCu0MLUzDpFJJQyOcyk0q8vAsNBMTMjd3-2uT7HbHLtmb7thI3nBOafiFycbUf4</recordid><startdate>19610101</startdate><enddate>19610101</enddate><creator>D. P. N. Tsao</creator><creator>J. A. 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J. De Feo</au><au>Youngken, H. W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Note on the Biological Activity of Root Extracts from Pleiocarpa mutica Benth. (Apocynaceae)</atitle><jtitle>Economic botany</jtitle><date>1961-01-01</date><risdate>1961</risdate><volume>15</volume><issue>1</issue><spage>99</spage><epage>103</epage><pages>99-103</pages><issn>0013-0001</issn><eissn>1874-9364</eissn><abstract>Several organic solvent and aqueous extractives were prepared from dried roots of Pleiocarpa mutica Benth. obtained from the Belgium Congo. All aqueous fractions produced a drop in blood pressure when administered to laboratory rats. A moist ethyl acetate extract produced most significant hypotensive activity. Preliminary tests indicate the presence of alkaloids in the active extracts of this species, and that the activity blocks the effect of epinephrine but is not altered by atropine. The active acetate fraction also destroyed adult and larvae stages of the nematode, Panagrellus redivivus (L.) Goody when added to test cultures.</abstract><pub>The New York Botanical Garden</pub><doi>10.1007/BF02906766</doi><tpages>5</tpages></addata></record> |
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| ispartof | Economic botany, 1961-01, Vol.15 (1), p.99-103 |
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| language | eng |
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| source | SpringerLink; JSTOR |
| subjects | Acetates Alkaloids Atropine Blood pressure Dosage Intravenous injections Nematode larvae Nematodes Pharmacology Solvents |
| title | A Note on the Biological Activity of Root Extracts from Pleiocarpa mutica Benth. (Apocynaceae) |
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