Specific Chromosomal Imbalances in Human Papillomavirus-Transfected Cells during Progression toward Immortality

High risk human papillomaviruses (HPVs) known to be closely associated with cervical cancer, such as HPV16 and HPV18, have the potential to immortalize human epithelial cells in culture. Four lines of HPV-transfected keratinocytes were analyzed by comparative genomic hybridization at different time...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1997-04, Vol.94 (8), p.3854-3859
Hauptverfasser:	Solinas-Toldo, Sabina, Durst, Matthias, Lichter, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences Cell culture techniques Cell Line Cell lines Cell Transformation, Viral - genetics Cellular biology Cervical cancer Chromosomes Chromosomes, Human - genetics Comparative genomic hybridization DNA Epithelial cells Genes Genetics Genome, Human Humans Keratinocytes Papillomaviridae Transfection Tumors Viruses
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