FoxO is a critical regulator of stem cell maintenance in immortal Hydra

Hydra ’s unlimited life span has long attracted attention from natural scientists. The reason for that phenomenon is the indefinite self-renewal capacity of its stem cells. The underlying molecular mechanisms have yet to be explored. Here, by comparing the transcriptomes of Hydra ’s stem cells follo...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2012-11, Vol.109 (48), p.19697-19702
Hauptverfasser:	Boehm, Anna-Marei, Khalturin, Konstantin, Anton-Erxleben, Friederike, Hemmrich, Georg, Klostermeier, Ulrich C, Lopez-Quintero, Javier A, Oberg, Hans-Heinrich, Puchert, Malte, Rosenstiel, Philip, Wittlieb, Jörg, Bosch, Thomas C. G
Format:	Artikel
Sprache:	eng
Schlagworte:	adenosine monophosphate Animals Animals, Genetically Modified antimicrobial peptides Aquatic life Biological Sciences Cell growth Cell Lineage Cell lines cell proliferation Epithelial cells Evolution Forkhead Transcription Factors - genetics Forkhead Transcription Factors - physiology Gene expression gene expression regulation gene overexpression Gene Silencing genes genetically modified organisms humans Hydra Hydra - cytology Hydra - immunology Hydra - metabolism Immunity, Innate Interstitial cells Life span Longevity Molecular Sequence Data Neural stem cells Peptides population growth Proteins Somatic cells Stem cells Stem Cells - metabolism Transcription factors transcriptome
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