Enhanced humoral immune responses against T-independent antigens in Fcα/μR-deficient mice

IgM is an antibody class common to all vertebrates that plays a primary role in host defenses against infection. Binding of IgM with an antigen initiates the complement cascade, accelerating cellular and humoral immune responses. However, the functional role of the Fc receptor for IgM in such immune...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2009-07, Vol.106 (27), p.11230-11235
Hauptverfasser:	Honda, Shin-ichiro, Kurita, Naoki, Miyamoto, Akitomo, Cho, Yukiko, Usui, Kenta, Takeshita, Kie, Takahashi, Satoru, Yasui, Teruhito, Kikutani, Hitoshi, Kinoshita, Taroh, Fujita, Teizo, Tahara-Hanaoka, Satoko, Shibuya, Kazuko, Shibuya, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens B lymphocytes Biological Sciences Fc receptors Immunization Lymphoid tissue Mice Receptors Spleen T lymphocytes
Online-Zugang:	Volltext
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