A Precise Reconstruction of the Emergence and Constrained Radiations of Escherichia coli 0157 Portrayed by Backbone Concatenomic Analysis

Single nucleotide polymorphisms (SNPs) in stable genome regions provide durable measurements of species evolution. We systematically identified each SNP in concatenations of all backbone ORFs in 7 newly or previously sequenced evolutionarily instructive pathogenic Escherichia coli OI57:H7, OI57: H⁻,...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2009-05, Vol.106 (21), p.8713-8718
Hauptverfasser:	Leopold, Shana R., Magrini, Vincent, Holt, Nicholas J., Shaikh, Nurmohammad, Mardis, Elaine R., Cagno, Joseph, Ogura, Yoshitoshi, Iguchi, Atsushi, Hayashi, Tetsuya, Mellmann, Alexander, Karch, Helge, Besser, Thomas E., Sawyer, Stanley A., Whittam, Thomas S., Tarr, Phillip I., Curtiss, Roy
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriophages Descendants Escherichia coli Evolution Genetic mutation Genomes Nucleotides Open reading frames Pathogens Sequencing
Online-Zugang:	Volltext
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