Creutzfeldt-Jacob Disease Associated with the PRNP Codon$200^{{\rm LYS}}$Mutation: An Analysis of 45 Families

$200^{{\rm Lys}}$mutation in the human PRNP coding region has been identified in 45 of the 55 CJD-affected families thus far presented to our NIH laboratory. These codon$200^{{\rm Lys}}$families have a total of 87 patients, and originate from 7 different countries: Slovakia, Poland, Germany, Tunisia...

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Veröffentlicht in:	European journal of epidemiology 1991-09, Vol.7 (5), p.477-486
Hauptverfasser:	Goldfarb, L. G., Brown, P., Mitrovà, E., Cervenáková, L., Goldin, L., Korczyn, A. D., Chapman, J., Gálvez, S., Cartier, L., Rubenstein, R., Gajdusek, D. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Codons Creutzfeldt Jakob syndrome Diseases of Humans: Creutzfeldt-Jakob Disease and the Gerstmann-Sträussler-Scheinker Syndrome (Genetics) DNA Epidemiology Genetic mutation Nervous system diseases Nucleotides Sephardic Jews Siblings
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