Repression of Phase-Variable cup Gene Expression by H-NS-Like Proteins Pseudomonas aeruginosa

The cupA gene cluster of Pseudomonas aeruginosa encodes components of a putative fimbrial structure that enable this opportunistic human pathogen to form biofilms on abiotic surfaces. In P. aeruginosa, cupA gene expression is repressed by MvaT, a putative transcription regulator thought to belong to...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2005-08, Vol.102 (31), p.11082-11087
Hauptverfasser:	Vallet-Gely, Isabelle, Donovan, Katherine E., Fang, Rui, Joung, J. Keith, Dove, Simon L., Mekalanos, John J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial proteins Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Biofilms Biological Sciences Chimeras DNA-Binding Proteins - chemistry DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Gene expression Gene Expression Regulation, Bacterial Genes Genes, Bacterial Microbiology Multigene family Overproduction Pathogens Plasmids Proteins Pseudomonas aeruginosa Pseudomonas aeruginosa - genetics Pseudomonas aeruginosa - metabolism Regulator genes Repression Trans-Activators - chemistry Trans-Activators - genetics Trans-Activators - metabolism Two-Hybrid System Techniques
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