Network Motifs in Integrated Cellular Networks of Transcription-Regulation and Protein-Protein Interaction

Genes and proteins generate molecular circuitry that enables the cell to process information and respond to stimuli. A major challenge is to identify characteristic patterns in this network of interactions that may shed light on basic cellular mechanisms. Previous studies have analyzed aspects of th...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2004-04, Vol.101 (16), p.5934-5939
Hauptverfasser:	Yeger-Lotem, Esti, Sattath, Shmuel, Kashtan, Nadav, Itzkovitz, Shalev, Milo, Ron, Pinter, Ron Y., Alon, Uri, Margalit, Hanah, Kopell, Nancy J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Biological Sciences Control loops Datasets Gene Expression Regulation Genes Nucleic acids Protein Binding Proteins - chemistry Proteins - genetics Proteins - metabolism Saccharomyces cerevisiae Statistical significance Transcription factors Transcription, Genetic Transcriptional regulatory elements Yeasts
Online-Zugang:	Volltext
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