Human Papillomavirus (HPV) Origin-Binding Protein Associates with Mitotic Spindles to Enable Viral DNA Partitioning

Human papillomaviruses (HPVs) establish long-term infections in patients. The mechanism for extrachromosomal HPV DNA persistence in cycling cells is unknown. We show that HPV origin-containing plasmids partition as minichromosomes, attributable to an association of the viral origin recognition prote...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2004-03, Vol.101 (12), p.4030-4035
Hauptverfasser: Van Tine, Brian A., Dao, Luan D., Wu, Shwu-Yuan, Sonbuchner, Timothy M., Lin, Biing Yuan, Zou, Nianxiang, Chiang, Cheng-Ming, Broker, Thomas R., Chow, Louise T., Lehman, I. Robert
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Sprache:eng
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