cDNA Sequence of Rat Liver Fructose-1,6-bisphosphatase and Evidence for Down-Regulation of Its mRNA by Insulin

A coding-length clone of rat liver fructose-1,6-bisphosphatase (EC 3.1.3.11) was isolated by immunological screening of a cDNA library in λ gt11. Its identity was verified by comparing the deduced amino acid sequence with that obtained by direct sequencing of a complete set of CNBr and proteolytic p...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1988-11, Vol.85 (22), p.8430-8434
Hauptverfasser:	El-Maghrabi, M. Raafat, Pilkis, Jo, Marker, Alison J., Colosia, Ann D., D'Angelo, Guy, Fraser, Blair A., Pilkis, Simon J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Analytical, structural and metabolic biochemistry Animals Base Sequence Biological and medical sciences Codon Complementary DNA Diabetes DNA - drug effects DNA - genetics Enzymes Enzymes and enzyme inhibitors Fructose-Bisphosphatase - genetics Fundamental and applied biological sciences. Psychology Insulin Insulin - pharmacology Kidneys Liver Liver - drug effects Liver - enzymology Messenger RNA Molecular Sequence Data Rats RNA RNA, Messenger - drug effects RNA, Messenger - genetics Sequence Homology, Nucleic Acid Transferases
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