Antibodies that Inhibit Fusion of Human Immunodeficiency Virus-Infected Cells Bind a 24-amino Acid Sequence of the Viral Envelope, gp120

Antisera to recombinant human immunodeficiency virus (HIV) proteins containing the entire envelope, gp160, or the central portion of the envelope, PB1, can inhibit fusion of virally infected cells in culture. This fusion inhibition is HIV-variant specific--that is, anti-gp160-IIIB inhibits fusion of...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1988-05, Vol.85 (9), p.3198-3202
Hauptverfasser:	Rusche, James R., Javaherian, Kashi, McDanal, Charlene, Petro, Joan, Lynn, Debra L., Grimaila, Raymond, Langlois, Alphonse, Gallo, Robert C., Arthur, Larry O., Fischinger, Peter J., Bolognesi, Dani P., Putney, Scott D., Matthews, Thomas J.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Amino Acid Sequence Amino acids Animals Antibodies Antiserum Biological and medical sciences Blood Cell fusion Cellular immunity Enzyme-Linked Immunosorbent Assay Epitopes Epitopes - analysis Fundamental and applied biological sciences. Psychology Giant cells HIV HIV - immunology HIV Envelope Protein gp120 Microbiology Pan troglodytes Proteins Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains Retroviridae Proteins - immunology Viral Fusion Proteins - antagonists & inhibitors Virology Viruses
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