Use of Sindbis Virus-Mediated RNA Interference to Demonstrate a Conserved Role of Broad-Complex in Insect Metamorphosis

The transcription factor Broad-Complex (BR-C) is required for differentiation of adult structures as well as for the programmed death of obsolete larval organs during metamorphosis of the fruit fly Drosophila melanogaster. Whether BR-C has a similar role in other holometabolous insects could not be...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2003-12, Vol.100 (26), p.15607-15612
Hauptverfasser:	Uhlirova, Mirka, Foy, Brian D., Beaty, Barry J., Olson, Ken E., Riddiford, Lynn M., Jindra, Marek
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult insects Animals Base Sequence Biological Sciences Bombyx - growth & development Bombyx mori Broad-Complex protein Chlorocebus aethiops Complementary DNA Cricetinae Culicidae DNA Primers Drosophila Drosophila melanogaster Drosophila melanogaster - growth & development Drosophila Proteins - metabolism Eye - growth & development Insect genetics Insect larvae Larva Larval development Metamorphosis Metamorphosis, Biological Molecular Sequence Data Pupa Pupae RNA RNA, Small Interfering - pharmacology RNA, Small Interfering - physiology RNA, Viral - physiology Sindbis virus Sindbis Virus - genetics Transcription Factors - metabolism Vero Cells Viruses
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