Genomic imprinting of two antagonistic loci

We present a model that considers the coevolution of genomic imprinting at a growth factor locus and an antagonistic growth suppressor locus. With respect to the two loci considered independently, our model makes the familiar predictions that an imprinted growth factor locus will only be expressed f...

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Veröffentlicht in:	Proceedings of the Royal Society. B, Biological sciences Biological sciences, 2001-09, Vol.268 (1479), p.1861-1867
Hauptverfasser:	Wilkins, Jon F., Haig, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Antagonistic Coevolution Ecological competition Evolution Evolutionary Stability Genetic loci Genetic mutation Genomic Imprinting Growth Factor Growth Suppressor Humans Igf2 Insulin-Like Growth Factor II - genetics Mammals Models, Genetic Receptor, IGF Type 2 - genetics Receptors Somatomedins Taxa
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