T Lineage Differentiation from Human Embryonic Stem Cells

Harnessing the ability of genetically manipulated human embryonic stem cells (hESC) to differentiate into appropriate lineages could revolutionize medical practice. These cells have the theoretical potential to develop into all mature cell types; however, the actual ability to develop into all hemat...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2006-08, Vol.103 (31), p.11742-11747
Hauptverfasser:	Galić, Zoran, Kitchen, Scott G., Kacena, Amelia, Subramanian, Aparna, Burke, Bryan, Cortado, Ruth, Zack, Jerome A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD - metabolism Biological Sciences Bone marrow Cell Differentiation - physiology Cell Lineage Cell lines Cells Cells, Cultured Coculture Techniques Cultured cells Embryo, Mammalian - cytology Gene expression Gene therapy Genetic disorders Hematopoietic stem cells Humans Lymphocytes Mice Mice, SCID Natural killer cells Progenitor cells Skin & tissue grafts Stem Cell Transplantation Stem cells Stem Cells - cytology Stem Cells - physiology Stromal cells Stromal Cells - cytology Stromal Cells - physiology T lymphocytes T-Lymphocytes - cytology T-Lymphocytes - physiology Thymocytes Tissue Transplantation
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