A Large Region (≈ 95 kDa) of Human Factor VIII is Dispensable for in vitro Procoagulant Activity

Factor VIII (antihemophilic factor) is a high molecular weight plasma glycoprotein that participates in the blood clotting cascade. The recent cloning and sequence analysis of the cDNA encoding human factor VIII revealed an obvious domain structure for the protein, which can be represented as A1-A2-...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1986-08, Vol.83 (16), p.5939-5942
Hauptverfasser:	Toole, John J., Pittman, Debra D., Orr, Elizabeth C., Murtha, Patricia, Wasley, Louise C., Kaufman, Randal J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Base Sequence Biological and medical sciences Biological Evolution Blood Coagulation Blood coagulation. Blood cells Coagulation factors Complementary DNA COS cells DNA DNA Restriction Enzymes Exons Factor VIII - genetics Factor VIII - metabolism Fundamental and applied biological sciences. Psychology Genes Humans Molecular and cellular biology Molecular Weight Molecules Nucleotides Plasmids Transfection
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