Plasmodium falciparumchloroquine resistance transporter is a H⁺-coupled polyspecific nutrient and drug exporter

Extrusion of chloroquine (CQ) from digestive vacuoles through thePlasmodium falciparumCQ resistance transporter (PfCRT) is essential to establish CQ resistance of the malaria parasite. However, the physiological relevance of PfCRT and how CQ-resistant PfCRT gains the ability to transport CQ remain u...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2015-03, Vol.112 (11), p.3356-3361
Hauptverfasser:	Juge, Narinobu, Moriyama, Sawako, Miyaji, Takaaki, Kawakami, Mamiyo, Iwai, Haruka, Fukui, Tomoya, Nelson, Nathan, Omote, Hiroshi, Moriyama, Yoshinori
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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