Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza

The immune responses to influenza, a virus that exhibits strain variation, show complex dynamics where prior immunity shapes the response to the subsequent infecting strains. Original antigenic sin (OAS) describes the observation that antibodies to the first encountered influenza strain, specificall...

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Veröffentlicht in:	Philosophical transactions of the Royal Society of London. Series B. Biological sciences 2015-09, Vol.370 (1676), p.1-10
Hauptverfasser:	Zarnitsyna, Veronika I., Ellebedy, Ali H., Davis, Carl, Jacob, Joshy, Ahmed, Rafi, Antia, Rustom
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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