Structural Gene for β -nerve Growth Factor not Defective in Familial Dysautonomia

The developmental loss of neurons in sympathetic, sensory, and some parasympathetic ganglia in familial dysautonomia suggests an inherited defect in the action of β -nerve growth factor (β -NGF). The role of this growth factor in dysautonomia has been difficult to resolve as there is no known source...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1984-07, Vol.81 (13), p.4211-4214
Hauptverfasser: Breakefield, Xandra O., Orloff, Gregory, Castiglione, Carmela, Coussens, Lisa, Axelrod, Felicia B., Ullrich, Axel
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Sprache:eng
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