Long-term potentiation of glycinergic synapses triggered by interleukin 1β

Long-term potentiation (LTP) is a persistent increase in synaptic strength required for many behavioral adaptations, including learning and memory, visual and somatosensory system functional development, and drug addiction. Recent work has suggested a role for LTP-like phenomena in the processing of...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2014-06, Vol.111 (22), p.8263-8268
Hauptverfasser:	Chirila, Anda M., Brown, Travis E., Bishop, Rachel A., Bellono, Nicholas W., Pucci, Francesco G., Kauer, Julie A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - physiology Biological Sciences drug abuse GABAergic Neurons - metabolism GABAergic Neurons - physiology gamma-aminobutyric acid gamma-aminobutyric acid receptors Glycine - metabolism Glycine receptors Hyperalgesia Hyperalgesia - metabolism Hyperalgesia - physiopathology Inflammation interleukin-1beta Interleukin-1beta - metabolism Interleukin-1beta - pharmacology Interleukin-1beta - physiology Interneurons Interneurons - metabolism Interneurons - physiology Long term potentiation Long-Term Potentiation - drug effects Long-Term Potentiation - physiology mammals memory Mice Mice, Inbred C57BL Mice, Knockout Neuralgia - metabolism Neuralgia - physiopathology Neuritis - metabolism Neuritis - physiopathology Neurons Organ Culture Techniques Pain Posterior Horn Cells - drug effects Posterior Horn Cells - metabolism Posterior Horn Cells - physiology Receptors Signal Transduction - physiology Spinal cord Spinal Cord - cytology Spinal Cord - drug effects Spinal Cord - physiology Synapses Synapses - physiology
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