mechanism for retromer endosomal coat complex assembly with cargo

Retromer is an evolutionarily conserved protein complex composed of the VPS26, VPS29, and VPS35 proteins that selects and packages cargo proteins into transport carriers that export cargo from the endosome. The mechanisms by which retromer is recruited to the endosome and captures cargo are unknown....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2014-01, Vol.111 (1), p.267-272
Hauptverfasser:	Harrison, Megan S., Hung, Chia-Sui, Liu, Ting-ting, Christiano, Romain, Walther, Tobias C., Burd, Christopher G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites Biological Sciences Biological Transport Carrier Proteins - chemistry Cell membranes Cross-Linking Reagents Endosomes Endosomes - metabolism Freight Genetic mutation Genetics guanosinetriphosphatase Humans Liposomes Liposomes - chemistry Mass Spectrometry Membranes Mutation P branes peripheral nervous system diseases phosphatidylinositol 3-kinase Phosphatidylinositol 3-Kinases - metabolism Protein Binding Protein Transport Proteins rab GTP-Binding Proteins - chemistry Recycling Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - chemistry Signal Transduction Sorting Nexins - chemistry transport proteins Vesicular Transport Proteins - chemistry Yeasts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!