Mechanosensory responses of osteocytes to physiological forces occur along processes and not cell body and require αVβ₃ integrin

Osteocytes in the lacunar–canalicular system of the bone are thought to be the cells that sense mechanical loading and transduce mechanical strain into biomechanical responses. The goal of this study was to evaluate the extent to which focal mechanical stimulation of osteocyte cell body and process...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2013-12, Vol.110 (52), p.21012-21017
Hauptverfasser: Thi, Mia M., Suadicani, Sylvia O., Schaffler, Mitchell B., Weinbaum, Sheldon, Spray, David C.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!