Cultured Adherent Cells from Marrow can Serve as Long-Lasting Precursor Cells for Bone, Cartilage, and Lung in Irradiated Mice

Cells from transgenic mice expressing a human mini-gene for collagen I were used as markers to follow the fate of mesenchymal precursor cells from marrow that were partially enriched by adherence to plastic, expanded in culture, and then injected into irradiated mice. Sensitive PCR assays for the ma...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1995-05, Vol.92 (11), p.4857-4861
Hauptverfasser:	Pereira, R. F., Halford, K. W., O'Hara, M. D., Leeper, D. B., Sokolov, B. P., Pollard, M. D., Bagasra, O., Prockop, D. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Animals B lymphocytes Base Sequence Bone and Bones - cytology Bone and Bones - radiation effects Bone marrow Bone Marrow Cells Bone Marrow Transplantation Bones Cartilage - cytology Cartilage - radiation effects Cell Adhesion Cell Differentiation Cells, Cultured Cesium Radioisotopes Chondrocytes Collagen - biosynthesis Collagen - genetics Cultured cells DNA Primers Endothelial cells Gene Expression Hematopoietic stem cells Humans Lung - cytology Lung - radiation effects Mesenchymal stem cells Mice Mice, Inbred Strains Mice, Transgenic Molecular Sequence Data Polymerase Chain Reaction - methods Stem Cells - cytology T lymphocytes
Online-Zugang:	Volltext
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