Cloning and Expression of a Human P2UNucleotide Receptor, a Target for Cystic Fibrosis Pharmacotherapy

The Cl-secretory pathway that is defective in cystic fibrosis (CF) can be bypassed by an alternative pathway for Cl-transport that is activated by extracellular nucleotides. Accordingly, the P2receptor that mediates this effect is a therapeutic target for improving Cl-secretion in CF patients. In th...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1994-04, Vol.91 (8), p.3275-3279
Hauptverfasser:	C. Edward Parr, Daniel M. Sullivan, Anthony M. Paradiso, Eduardo R. Lazarowski, Laranell H. Burch, John C. Olsen, Laurie Erb, Gary A. Weisman, Richard C. Boucher, John T. Turner
Format:	Artikel
Sprache:	lat
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!