Characterization of Immortal Cystic Fibrosis Tracheobronchial Gland Epithelial Cells

Tracheobronchial glands were isolated and cultured from a patient with cystic fibrosis (CF). Cultured epithelial cells were transformed with pSVori-. All transformed cell lines express cytokeratin filaments and at early passages express the junctional complex molecule cellCAM 120/80, indicating thei...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1992-06, Vol.89 (11), p.5171-5175
Hauptverfasser:	Cozens, A. L., Yezzi, M. J., Chin, L., Simon, E. M., Finkbeiner, W. E., Wagner, J. A., Gruenert, D. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Bronchi - pathology Calcium Calcium - metabolism Carbachol - pharmacology Cell lines Cell Transformation, Viral Cells, Cultured Cellular biology Chlorides - metabolism Cultured cells Cyclic AMP - metabolism Cystic fibrosis Cystic Fibrosis - pathology Cystic Fibrosis - physiopathology Cystic Fibrosis Transmembrane Conductance Regulator Epithelial cells Epithelium - pathology Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Genetic mutation Histamines Humans In Vitro Techniques Intestines Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Membrane Proteins - physiology Molecular Sequence Data Nasal polyps Oligodeoxyribonucleotides - chemistry Oligonucleotide Probes Other diseases. Semiology Polymerase Chain Reaction RNA, Messenger - genetics Simian virus 40 Trachea - pathology Transformed cell line
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