Transforming Growth Factor β Stimulates Urokinase-Type Plasminogen Activator and DNA Synthesis, but not Prostaglandin E2Production, in Human Synovial Fibroblast

Transforming growth factor β (TGF-β) is usually associated with matrix formation and tissue repair; in contrast, cellular expression of the serine proteinase, urokinase-type plasminogen activator (u-PA) is often correlated with tissue remodeling, as well as with cell migration and transformation. We...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1991-08, Vol.88 (16), p.7180-7184
Hauptverfasser: Hamilton, John A., Piccoli, Diana S., Leizer, Tali, Butler, Debra M., Croatto, Maryann, Royston, Keith M.
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Sprache:eng
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