Enhancement of Human Immunodeficiency Virus 1 Replication in Monocytes by 1,25-Dihydroxycholecalciferol

Human immunodeficiency virus (HIV) expression and replication are under tight regulatory control. We demonstrate that 1,25-dihydroxycholecalciferol [1,25-(OH)2D3] enhances the replication of monocyte- and lymphocyte-tropic strains of HIV-1 up to 10,000-fold in monocyte cell lines, peripheral blood m...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1991-08, Vol.88 (15), p.6632-6636
Hauptverfasser:	Skolnik, Paul R., Jahn, Beatrice, Wang, Monica Z., Rota, Teresa R., Hirsch, Martin S., Krane, Stephen M.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Antigens Antigens, CD - analysis Biological and medical sciences Blood Bone Marrow Calcitriol - pharmacology Cell culture techniques Cell Line Cell lines Cultured cells Fundamental and applied biological sciences. Psychology Gene Products, gag - analysis Genetics HIV HIV 1 HIV Core Protein p24 HIV-1 - drug effects HIV-1 - physiology HLA-DR Antigens - analysis Humans Infections Kinetics Microbiology Monocytes Receptors Receptors, Calcitriol Receptors, Steroid - physiology Viral Core Proteins - analysis Virology Virus Replication - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!