E-Cadherin-Dependent Growth Suppression Is Mediated by the Cyclin-Dependent Kinase Inhibitor p27 KIP1

Recent studies have demonstrated the importance of E-cadherin, a homophilic cell-cell adhesion molecule, in contact inhibition of growth of normal epithelial cells. Many tumor cells also maintain strong intercellular adhesion, and are growth-inhibited by cell-cell contact, especially when grown in t...

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Veröffentlicht in:	The Journal of cell biology 1998-07, Vol.142 (2), p.557-571
Hauptverfasser:	St. Croix, Brad, Sheehan, Capucine, Rak, Janusz W., Flørenes, Vivi Ann, Slingerland, Joyce M., Kerbel, Robert S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Cadherins Cell cycle Cell growth Cell lines Cells Cultured cells Cyclins Epithelial cells HT29 cells
Online-Zugang:	Volltext
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